ICG Fluorescence Imaging and Navigation Surgery by Mitsuo Kusano, Norihiro Kokudo, Masakazu Toi, Masaki Kaibori

By Mitsuo Kusano, Norihiro Kokudo, Masakazu Toi, Masaki Kaibori

This publication provides a finished assessment and outlook for the way forward for indocyanine eco-friendly (ICG) fluorescence navigation surgical procedure, that's attracting scientific curiosity as a secure and not more invasive process not just in detecting cerebral vessels, coronary arteries, and biliary bushes, but in addition in picking out sentinel lymph nodes in melanoma. The ebook starts off with the features of ICG and photodynamic cameras/endoscopes, by means of distinctive descriptions of the functions of ICG fluorescence imaging in a variety of components reminiscent of ocular surgical procedure, neurosurgery, cardiovascular surgical procedure, and cosmetic surgery. It additionally covers selecting sentinel lymph nodes in breast melanoma in addition to cancers of the gastrointestinal tract, and offers useful info for hepato-biliary-pancreatic surgeons, similar to opting for tattooing of liver segments and bile leakage. Written solely by means of specialists of their respective components, ICG Fluorescence Imaging and Navigation Surgery deals a vital source for surgeons working on cancers and vascular issues within the mind and cardiovascular structures and in plastic surgery.

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Thus, a camera capable of detecting infrared radiation is necessary for fluorescent imaging. ICG florescence imaging becomes possible by a system in which the camera irradiates infrared radiation with a specific wavelength and detects the ICG fluorescent wavelength. The development of ICG observing systems has led to its application in other medical fields. It has been used intraoperatively for cerebral angiography in neurosurgery [5, 6], coronary angiography in heart surgery [7], neck angiography in neck surgery [8], and visualization of lymph nodes in cancer surgery [9, 10].

Keywords Indocyanine green videoangiography • Neurosurgical procedure • Cerebral blood flow Y. D. jp H. D. • S. D. • T. D. Department of Neurosurgery, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime 791-0295, Japan © Springer Japan 2016 M. Kusano et al. 1 Y. Kumon et al. 96. In the body, ICG combined with lipoprotein in the blood is transported to liver, and it is absorbed into liver cells and excreted into the bile without metabolism. ICG has been used to examine liver cell function.

In the cryptic AVM hidden in the occipital sulcus, recognition of draining vein using ICG-VAG was useful to confirm the location of nidus (Fig. 5b, c, d). After removal of AVM (Fig. 5e), the draining vein was not shown on ICG-VAG image (Fig. 5f). These findings were confirmed using intraoperative DSA (Fig. 5a, g). Faber et al. reported the usefulness of FLOW 800 in two patients with frontal or temporal AVMs [37]. They concluded that color-coded analytical ICG-VAG with FLOW 800 enabled intraoperative real-time analysis of arterial and venous vessel architecture and might increase the efficacy and safety of neurovascular surgery in a selected subset of superficial AVMs.

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