The Vulnerable Atherosclerotic Plaque: Strategies for by Renu Virmani, Jagat Narula, Martin B. Leon, James T.

By Renu Virmani, Jagat Narula, Martin B. Leon, James T. Willerson

Eventually, a handy, one-volume precis of present wisdom on a space of accelerating significance! The weak Atherosclerotic Plaque provides contributions from the easiest investigators within the box, skillfully edited for simple interpreting and lavishly illustrated with high quality, full-color images.After a thought of and concise creation, the e-book concentrates on: Pathology of susceptible plaque Triggers for plaque rupture Imaging of risky plaque administration of susceptible plaques cautious enhancing permits the authors to prevent repetition and supply entire assurance of pathology, detection, and administration. This thorough and authoritative reference will switch the best way interventionists examine the ailment.

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Additional info for The Vulnerable Atherosclerotic Plaque: Strategies for Diagnosis and Management

Sample text

Circulation 1999;99:1965 –71. 4 In this overview, we will discuss what characterizes an arterial plaque that is vulnerable to rupture in addition to how plaque progression leads to severe stenosis. These critical issues may help define the causes of sudden coronary death and assist in the development of treatment options targeting the unstable plaque. Luminal thrombosis and acute coronary syndromes Patients with acute coronary syndromes typically present with unstable angina, acute myocardial infarction, and sudden coronary death.

4 Correlation of serum hs-CRP with immunohistochemical staining intensity of plaques with thin-cap fibroatheromas. ) CRP CRP staining intensity of plaques* Mean no. 3 *Staining intensity was assessed for macrophages and lipid core. A semiquantitative score of 0 – 4 was assigned to each section. A sum of the two scores resulted in an overall grading system of 0 – 8. Abbreviation: hs-CRP = high sensitivity C-reactive protein. myocardial infarction and are least common in plaque erosions or incidental noncoronary deaths.

11). In patients dying suddenly, however, the incidence is similar between both sexes. Incidental deaths or those from plaque erosion show the fewest number of TCFAs. The number of TCFAs by plaque morphology shows the highest 4 Mean Number of Thin-Cap Atheromas are associated with positive remodeling, while stable plaques (fibrous-rich lesions), total occlusions, and erosions all show negative remodeling. 11 Thin-cap fibroatheromas are most frequent in patients dying with acute myocardial infarction (MI), followed by sudden coronary death (SCD) victims and incidental disease.

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