Antisense Therapeutics by Wafik S. El-Deiry

By Wafik S. El-Deiry

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2002) Intramural delivery of advanced antisense oligonucleotides with infiltrator cathetor inhibits c-myc expression and intimal hyperplasia in the porcine. J. Am. Coll. Cardiol. 39(10), 1686–1691. 21. 21 Sheppard, R. and Eisenberg, M. J. (2001) Intracoronary radiotherapy for restenosis. N. Engl. J. Med. 344(4), 295–297. 22. , et al. (2000) Local paclitaxel delivery for the prevention of restenosis: biological effects and efficacy in vivo. J. Am. Coll. Cardiol. 35(7), 1969–76. 23. 23 Sousa, J.

2 Chung, O. and Unger, T. (1999) Angiotensin II receptor blockade and end-organ protection. Am. J. Hypertens. 12, S150–S156. 3. , et al. (2002) Polymorphisms in the angiotensinogen and angiotensin II type 1 receptor gene are related to change in left ventricular mass during antihypertensive treatment: results from the Swedish Antisense Therapeutics for Hypertension 4. 4 5. 5 6. 6 7. 7 8. 8 9. 9 10. 10 11. 11 12. 13. 13 14. 14 15. 15 16. 16 17. 17 61 Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA) trial.

1993) Chimeric renin-angiotensin system demonstrates sustained increase in blood pressure of transgenic mice carrying both human renin and human angiotensinogen genes. J. Biol. Chem. 268, 11,617–11,621. Davisson, R. , Stec, D. , et al. (1999) Novel mechanism of hypertension revealed by cell-specific targeting of human angiotensinogen in transgenic mice. Physiol. Genomics 1, 3–9. Merrill, D. , Thompson, M. , Carney, C. , et al. (1996) Chronic hypertension and altered baroreflex responses in transgenic mice containing the human renin and human angiotensinogen genes.

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