By Glen F King; C R Ganellin; Salvatore Guccione
The pharmaceutical has turn into more and more drawn to biologics from animal venoms as a possible resource for healing brokers in recent times, with a very emphasis on peptides. thus far six medications derived from venom peptides or proteins were licensed via the FDA, with 9 additional brokers at present being investigated in scientific trials. as well as those medications in authorized or complicated levels of improvement, many extra peptides and proteins are being studied in various levels of preclinical improvement. This particular e-book offers an up-to-the-minute and entire account of the opportunity of peptides and proteins from animal venoms as attainable therapeutics. subject matters lined contain chemistry and structural biology of animal venoms, proteomic and transcriptomic methods to drug discovery, bioassays, high-throughput monitors and aim identity, and reptile, scorpion, spider and cone snail venoms as a platform for drug improvement. Case reports are used to demonstrate tools and successes and spotlight matters surrounding management and different vital classes which were learnt from the improvement of licensed therapeutics in accordance with venoms. the 1st textual content to target this attention-grabbing region and bridging a massive hole, this ebook will provide the reader with crucial and present wisdom in this fast-developing quarter. Venoms to medicinal drugs will locate large readership with researchers operating in academia and operating in all medicinal and pharmaceutical areas.
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