STRATEGIES IN THE DESIGN OF ANTIVIRAL DRUGS by Erik De Clercq

By Erik De Clercq

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Auerbach PS. Carroll PR (1989) Radiographic assessment of renal trauma: a 10year prospective study of patient selection. J Urol 141:10951098 Mirvis SE. Gens DR. Shanmuganathan K (1992) Rupture of the bowel after blunt abdominal trauma: diagnosis with CT. AJR Am J RoentgenoI159:1217-1221 Nunez D. Becerra JL. Fuentes D. Pagson S (1996) Traumatic occlusion of the renal artery: Helical CT diagnosis. AJR Am J RoentgenoI167:777-780 Orwig OS. Jeffrey RB Jr (1987) CT of false-negative peritoneal lavage following blunt abdominal trauma.

Radiology 173: 143-148 Roberts JL. Dalen K. Bosanko CM. Jafir SZH (1993) CT in abdominal and pelvic trauma. Radiographics 13:735-752 Sandler CM. Hall JT. Rodriguez MB. Corriere IN (1986) Bladder injury in blunt pelvic trauma. Radiology 158:633-638 Wolfman NT. Bechtold RE. Scharling ES. Meredith JW (1992) Blunt upper abdominal trauma: evaluation by CT. A. Sclafani Department of Radiology, Kings County Hospital Center. Brooklyn. NY. USA Introduction Head, abdominal and pelvic injuries account for the vast majority of deaths resulting from trauma.

Angiography has a role in assessing the degree of active hemorrhage and this appears to facilitate triage into operative and nonoperative cases. If arteriography shows no contrast extravasation, then it is highly 52 Fig. 4. Liver laceration resulting in a grade II liver injury predictive of successful nonoperative treatment. However, if extravasation is noted, then some form of intervention is required. Embolization of the proximal splenic artery with a coil or superselective embolization of the bleeding branch have both been shown to successfully control hemorrhage.

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