By Elizabeth Kwong
Detailing formula techniques through degree of discovery to early improvement, this ebook provides a “playbook” of functional and effective techniques to formulate drug applicants with the least likelihood of failing in scientific improvement.
• Comes from contributing authors with adventure constructing formulations at the frontlines of the pharmaceutical industry
• Focuses on pre (or non-) scientific and early level improvement, the stages the place such a lot compounds are utilized in drug research
• Features case reviews to demonstrate functional demanding situations and strategies in formula selection
• Covers regulatory submitting, drug metabolism and actual and chemical houses, toxicology formula, biopharmaceutics class approach (BCS), screening ways, early degree medical formula improvement, and outsourcing
Read or Download Oral Formulation Roadmap from Early Drug Discovery to Development PDF
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Extra info for Oral Formulation Roadmap from Early Drug Discovery to Development
1 Introduction Drug discovery lead optimization is usually a stage wherein the search for a good preclinical candidate is selected. At this stage, a good balancing act of optimizing potency, pharmacokinetics (PK) behavior and pharmacodynamics (PD), and toxicity is performed. To explore acceptable toxicology profile, the Oral Formulation Roadmap from Early Drug Discovery to Development, First Edition. Edited by Elizabeth Kwong. © 2017 John Wiley & Sons, Inc. Published 2017 by John Wiley & Sons, Inc.
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