By H.S. Thomsen (Editor)
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Extra resources for Contrast Media: Safety Issues and ESUR Guidelines (Medical Radiology Diagnostic Imaging)
Sample text
Radiol Technol 58:1245–1251 Atasoy M, Erdem T, Sari RF (2003) A case of acute generalized exanthematous pustulosis (AGEP) possibly induced by iohexol. J Dermatol 30:723–726 Bartolucci F, Cecarini M, Gabrielli G et al (2000) Reazioni tardive a un mezzo di contrasto radiologico (iopamidolo Bracco). Radiol Med 100:273–278 Bertrand P, Delhommais A, Alison D, Rouleau P (1995) Immediate and delayed tolerance of iohexol and ioxaglate in lower limb phlebography: a double-blind comparative study in humans.
In another study of patients with a variety of causes of reduced renal function, contrast medium induced nephropathy developed in 4% after the iso-osmolar nonionic dimer iodixanol and in 10% after a low-osmolar nonionic monomer (Chalmers and Jackson 1999). In a third study, contrast medium induced nephropathy developed in 17% of patients with severe renal impairment who received intravenous injection of either a nonionic monomer or an iso-osmolar dimer for body or cranial CT but full details of the study have never been published (Kolehmainen and Soiva 2003).
5 mg/dl)] have minimal risk (Rudnick et al. 1995; McCullough et al. 1989; Parfrey et al. 1989; Thomsen et al. 2005). 2 When Should Serum Creatinine Be Measured? A questionnaire designed to elicit a history of renal disorders as well as additional risk factors for contrast medium induced nephropathy may be used to identify patients with normal serum creatinine in whom blood testing would be unnecessary (Choyke et al. 1998). 4 mg/dl) for men]. 7 mg/dl). There was a strong association between raised serum creatinine values and a history of renal disease, proteinuria, prior kidney surgery, hypertension, gout and diabetes.