Tinnitus - A Medical Dictionary, Bibliography, and Annotated by Icon Health Publications

By Icon Health Publications

This can be a 3-in-1 reference publication. It offers a whole scientific dictionary protecting hundreds and hundreds of phrases and expressions when it comes to tinnitus. It additionally supplies vast lists of bibliographic citations. eventually, it presents details to clients on the way to replace their wisdom utilizing quite a few net assets. The ebook is designed for physicians, scientific scholars getting ready for Board examinations, scientific researchers, and sufferers who are looking to familiarize yourself with learn devoted to tinnitus. in case your time is effective, this ebook is for you. First, you won't waste time looking out the web whereas lacking loads of appropriate info. moment, the e-book additionally saves you time indexing and defining entries. eventually, you won't waste money and time printing 1000s of web content.

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Sample text

Recently we have identified a previously unreported sensory innervation of the cochlear blood vessels originating from the trigeminal ganglia. , in the animal model of endolymphatic hydrops, one of the symptoms of Meniere's disease). This proposal seeks to further define the anatomical basis and mechanisms of the trigemino-sensory network around the vertebrovasilar and cochlear vascular system. The proposal offers the hypothesis that the trigemino-sensory system and its related neuropeptide system are important factors contributing to basilar migraine and vascular homeostasis of the cochlea.

Their fine structure and lack of astrocytic processes having high-affinity glutamate transporters may endow the nests with an unusual potential for producing plastic changes to ongoing stimulation and to damaging levels of noise. A specific hypothesis is that overstimulation produces structural and histochemical changes, including chronic degeneration and new growth of synaptic endings in the nests and the regions associated with them. To see if the balance of excitatory and inhibitory input is thereby disturbed, the analysis will focus on the relative proportions of the different types of synaptic ending in the nests, the transmitter-related molecules associated with them, their origins, and the plastic changes they undergo in response to noise damage.

In Specific Aim III, we plan to evaluate sensory function of the paw in rat models of pain after sciatic nerve injury. At sacrifice, biopsies will be taken from the bottom of the rat's paws as well as from the injured nerves to see whether changes in the density of nociceptive nerve endings in the foot correlate with severity of damage in the nerve and with the rat's behavior during sensory testing. The goal of this research is to improve medical care for patients with chronic neuropathic pain, and facilitate research by identifying "biomarkers" that can be used as surrogate measures for the presence of neuropathic pain.

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