By A. G. Dickinson, H. Fraser (auth.), Volker ter Meulen M.D., Michael Katz M.D. (eds.)
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Additional info for Slow Virus Infections of the Central Nervous System: Investigational Approaches to Etiology and Pathogenesis of These Diseases
Range of movement in forelimbs in walking: left, normal chimpanzee; right, chimpanzee in the second stage of experimental kuru. Quantitative assessment was made by studying individual frames of Research Cinema Film [from Gajdusek and Gibbs ( 19)]. 3 I Species of Labaratory Primates Susceptible to the Subacute Spongiform Virus Encephalopathiesn OF MAN Kuru Creutzfeldt-J akob disease chimpanzee, gibbon Apes capuchin, mam1oset, New World monkeys spider, squirrel, woolly cynomolgus macaque, Old W orld monkeys mangabey, rhesus, pig-tailed macaque chimpanzee Apes capuchin, mmmoset, New World monkeys spider, squirrel, woolly African green, baboon, Old W orld monkeys bushbaby, cynomolgus macaque, mangabey, patas, pig-tailed macaque, rhesus, stump-tailed macaque, talapoin OF ANIMALS Serapie Transmissihle mink encephalopathy a N ew W orld monkeys Old W orld monkeys rhesus N ew W orld monkeys Old W orld monkeys macaque capuchin, spider, squirrel cynomolgus macaque, squirrel rhesus, stump-tailed As of July 1, 1975.
Five children with kuru : two boys in the center, a girl on each side; the adolescent boy supporting the girl on the left is a kuru victim himself, but in an earlier stage of the disease. All are just passing from the first, or ambulatory, to the second, or sedentary, stage of the disease, and can no Ionger stand without support. cases show such plaques; they are also found in kuru and Alzheimer's disease. In addition, CJD and the other diseases have status spongiosus and astrogliosis ( 37, 38, 46).
Wiesenfeld, S. , Roos, R. , Bobowick, A. , Gibbs, C. , and Gajdusek, D. C. ( 1974). Familial Creutzfeldt-Jakob disease: Transmission of the familial disease to primates. In Proceedings of the Tenth International Congress of Neurology (A. Subirana and J. M. ), pp. 358-380. Excerpta Medica International Congress Series No. 319, Amsterdam. 13. Gajdusek, D. C. (1963). Motor-neuron disease in natives of New Guinea. New Engl. ]. Med. 268, 474-476. 14. Gajdusek, D. C. ( 1972). Spongiform virus encephalopathies.