By Martin Samuels, Allan H. Ropper MD
This pocket-size guide examines crucial diagnostic standards for every neurological sickness, and recommends techniques to remedy. There are charts to assist in deciding upon the proper drug and dosage. This up-to-date variation comprises the pharmacologic brokers lately authorized for the therapy of neurologic issues together with: migraine, epileptic seizures and standing epilepticus, acute stroke, Alzheimer disorder and neurological manifestations of HIV. additionally coated are new stereotactic radiosurgical ways to mind tumour therapy, pallidotomy and numerous deep mind stimulation options for sufferers with Parkinson illness and diagnostic checking out for genetically made up our minds neurological ailments.
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Extra info for Manual of Neurologic Therapeutics
Diamond S. Headache. Med Clin North Am 1991;75:521. Klapper JA. Toward a standard drug formulary for the treatment of headache. Headache 1995;35:225. Lance JW. The mechanism and management of headache, 5th ed. London: Butterworth, 1993. Raskin NH. Headache, 2nd ed. New York: Churchill Livingstone, 1988. Migraine and Cluster Headaches Cady RK, et al. Treatment of acute migraine with subcutaneous sumatriptan. JAMA 1991;265:2831. Feniuk W, et al. Rationale for the use of 5HT-like agonists in the treatment of migraine.
Occasionally, a shunting procedure is necessary to control the hydrocephalus. C. Headache occurs with a variety of intracranial mass lesions such as subdural hematoma (Chap. 12), brain tumor (Chap. 11), and brain abscess (Chap. 8). The headache of brain tumors is usually paroxysmal at first (often worse early in the morning, on arising). Later, the headaches become unremitting and may be complicated by vomiting. The initial side of the headache may reflect the side of the tumor, but this is not a highly reliable sign.
Ibuprofen (Motrin), 400 mg tid, may be effective migraine prophylaxis in some patients. Other NSAIDs appear to have comparable efficacy. Chronic use of ergotamines often leads to undesirable side effects. Rarely, prolonged usage of ergotamine leads to ischemic complications. As other effective preventive therapies have emerged, the use of methysergide (Sansert) as migraine prophylaxis has declined. About three fourths of patients respond favorably to methysergide (4 to 8 mg daily in divided doses).