Introduction to tissue engineering : applications and by Ravi Birla

By Ravi Birla

"Covering a revolutionary clinical box, Tissue Engineering describes the cutting edge strategy of regenerating human cells to revive or identify basic functionality in faulty organs. As pioneering participants watch for the potential for producing complete organ platforms, scholars may well flip to this textbook for a entire knowing and instruction for the way forward for regenerative medication. This publication explains Read more...


masking a revolutionary clinical box, Tissue Engineering describes the cutting edge means of regenerating human cells to revive or determine basic functionality in faulty organs. Read more...

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The recent expansion in the field of stem cell biology has provided researchers with many different options for cell sourcing, some of which include embryonic stem cells, induced pluripotent stem cells, and adult derived stem cells (hematopoietic stem cells and bone marrow derived mesenchymal stem cells). 3 Process of Fabricating 3D Artificial Tissue and Organs—(a) Step 1—Cell Sourcing—the first step in the process is the isolation and/or expansion of cells, which serve to provide function for artificial tissue and organs.

Often, tissue engineering has been defined as the ability to generate functional 3D tissue constructs in vitro, with potential 8 INTRODUCTION TO TISSUE ENGINEERING clinical applications to replace, restore and/or augment lost tissue function. , through the use of gene and/or cell transplantation. Certain authors define regenerative medicine as a broader field, with tissue engineering being one branch. Although a diversity of definitions has evolved in the recent literature, each one provides a novel insight into the field of tissue engineering.

As another example, bioartificial hearts can be used as transplantable organs for patients with end-stage heart failure, thereby providing a life-saving option for many patients across the globe. The purpose of the discussion presented in this section was to illustrate the tissue engineering paradigm using the cardiovascular system as an example. As we have seen, tissue engineering strategies can be applied toward the fabrication of artificial hearts and components of the cardiovascular system that can be used to repair, replace or augment the functional performance of comprised hearts.

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