By Stephen T Sonis (auth.)
Treatment tolerance is a problem for many melanoma sufferers, and it truly is consequently crucial that healthcare pros (HCP) are quickly to acknowledge adversarial occasions and enforce administration thoughts to deal with them. This notebook presents an in-depth consultant to the epidemiology, analysis and administration of oral mucositis, a standard opposed occasion of chemotherapy.
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Sample text
4 Mucositis research instruments. Mucositis research scales were developed in an attempt to provide quantitative, highly objective endpoints for mucositis assessment. They vary widely in complexity from a 34-item Oral Mucositis Index [7], to a 16-item scale [8] to an Oral Mucositis Assessment Scale that evaluates ulceration and erythema [6]. These scales all share quantitative outcomes to which statistical analyses can be easily applied. However, the interpretation of data by clinicians is often difficult.
The ideal mucositis scale It would be very desirable to have a single scale to describe mucositis severity. At the moment there are well over a dozen different scoring instruments that are used, and having no consistent and universally used scale is a detriment when comparing regimen toxicities or evaluating new agents. Consequently, although a single scoring system would be ideal, it is probably a long way off. 6 gives the key characteristics of the ideal mucositis scale. Variability between mucositis scales Interestingly, the severity of mucositis is not evenly reflected across scales.
Yes No Yes No Yes No Appearance 6. Please ask an adult to look in your mouth. Can he or she see any mouth sores in your mouth today? 4 Children’s International Mucositis Evaluation Scale (ChIMES). Reproduced with permission from Tomlinson et al [7]. Chapter 8 Nonmucositis mouth lesions in patients being treated for cancer Patients receiving cancer treatment, especially myelosuppressive chemotherapy, are at risk of developing oral lesions exclusive of mucositis. The most common are those associated with opportunistic mucosal infections and, in the case of allogeneic HSCT recipients, oral lesions of graft-versushost disease (GVHD).