New Trends in Hepatology: The Proceedings of the Annual by M. U. Dianzani (auth.), Paolo Gentilini, Mario Umberto

By M. U. Dianzani (auth.), Paolo Gentilini, Mario Umberto Dianzani (eds.)

The Italian crew for the examine of Liver Cirrhosis begun its job in 1980 at the foundation of popularity and monetary help from the Italian Ministry of the collage, medical examine and know-how, having been selected from a number of different clinical courses. the crowd is now referred to as the nationwide crew for the learn of Liver Cirrhosis and Viral Hepatitis and contains greater than forty facilities during the country less than the auspices of the colleges. the first Imtlatlve of the gang, to mix experimental and scientific ways within the learn of liver pathophysiology, is still unchanged. Annual conferences in January give you the chance of evaluating experimental and scientific ends up in the spirit of mutual comprehension and feedback. After 15 years and six volumes (published biannually), the particular development of Italian learn in liver pathophysiology is obvious. in truth, which will enable different researchers be aware of what has been completed we selected to post the seventh quantity, despite the commercial problems to hand. now we have collected particular reviews of all of the facilities incorporated within the nationwide software. each one workforce used to be required to provide an replace in its personal box of analysis, instead of particular or lately got effects, which may were stated in simple terms in courting with different information already released through others. just like the sixth variation in our sequence, this quantity affirms the categorical competence of all of the members and summarizes an important updates in liver pathophysiology.

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Department ofMedical Sciences and #Experimental Medicine and Oncology, University of Turin, Turin, Italy. Summary In spite of decades of researches the biochemical mechanisms responsible for the hepatotoxic action consequent to alcohol abuse have not yet been completely elucidated [1]. Acetaldehyde, the main product of ethanol oxidation, is generally considered to be main responsible for the damaging effects associated to alcohol abuse [1]. In recent years, however, an increasing number of studies have suggested that, beside acetaldehyde, free radical intermediates might be involved in the pathogenesis of alcohol toxicity.

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Lipid peroxidation and antioxidant defence systems in rat liver after chronic ethanol feeding. Hepatology 1989;10:815-821. 10. Wieland P, Lauterburg BH. Oxidation of mitochondrial proteins and DNA following administration of ethanol. Biochem Biophys Res Commun 1995;213:815-819. 11. Vendemiale G, Guerrieri F, Grattagliano I, Didonna I, Muoio L, Altomare E. Mitochondrial oxidative phosphorylation and intracellular glutathione compartmentation during rat liver regeneration. Hepatology 1995;21: 1450-1454.

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