Imaging Endocrine Diseases in Children by F. E. Avni, F. Rypens, M. Cassart (auth.), Fred Avni (eds.)

By F. E. Avni, F. Rypens, M. Cassart (auth.), Fred Avni (eds.)

This booklet is a distinct source that might support pediatric radiologists, pediatricians, and pediatric endocrinologists to optimize the work-up and therapy of pediatric sufferers with endocrine issues. Acclaimed specialists within the box current and talk about the imaging findings received in problems of a few of the endocrine platforms, together with the hypothalamo-pituitary axis, the thyroid and parathyroids, the adrenals, and the pancreas. certain recommendation is usually supplied at the evaluate of bone development and on imaging of the fetal glands, ambiguous genitalia, and the feminine pelvis within the context of precocious puberty. all through, care is taken to focus on attribute findings and diagnostic clues. all the at the moment used imaging thoughts are coated, with transparent clarification in their advantages and barriers. The informative textual content is supported via a wealth of high quality illustrations, the big majority of them in color.

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Sample text

T4 and T3 are then released into the blood circulation, while dehalogenase, present in thyrocytes as well as in extrathyroidal tissues, catalyses deiodination of monoiodotyrosine and diiodotyrosine. The released iodide is partly reused by the thyrocytes, and partly excreted via the kidney. Normally T4 and T3 are secreted by the thyroid in a ratio of approximately 4:1 (Kopp 2005). Thyroid hormone synthesis and release is controlled by thyrotropin (TSH, thyroid stimulating hormone) from the 40 Fig.

A giant, solid, invasive prolactinoma in a prepubescent child is extremely rare (Dinc et al. 2008; Furtado et al. 2010). Macroadenomas show intermediate signal in unenhanced T1-weighted images and enhance after contrast medium administration (Fig. 16). Invasion of the cavernous sinus is sometimes demonstrated but with normal carotid artery diameter. Pituitary apoplexy must be considered in case of intense headache and worsening visual acuity. MRI showed a large suprasellar mass with a small sellar component, with heterogeneous hyperintensity on T1-weighted images, suggestive of recent hemorrhage (Fig.

Rapid progression of pituitary hyperplasia may develop in case of peripheral hypothyroidism and evaluation of thyroid function is needed when a homogeneous pituitary mass is revealed by MR imaging; this hyperplasia disappears in a few months after substitutive treatment (Lee et al. 2008). 24 P. Bessou et al. Fig. 13 a Girl, 10-year-old, precocious puberty: bone age: 14-year-old. 1 Pituitary Adenomas Pituitary adenomas are relatively uncommon in children and account for less than 3 % of all supratentorial tumors.

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