By Robert Morfin
DHEA and the mind experiences a number of current reviews relating to DHEA management to animals and people. bankruptcy authors evaluation DHEA metabolism in tissues and organs, discover DHEA results within the liver which may be of value to the mind, and speak about contemporary findings concerning how DHEA is made within the mind. New views concerning the neuroprotective results of DHEA are awarded, in addition to perception on the topic of DHEA metabolism within the brain.A variety of wellbeing and fitness merits were linked to dehydroepiandrosterone (DHEA), together with anti-cancer, anti-osteoporosis, anti-atherosclerosis, anti-diabetes, immuno-stimulating, and memory-enhancing results. This has brought on hundreds of thousands of individuals to take this hormone as a regular dietary complement. besides the fact that, there's a few problem that lengthy self-administration may end up in health and wellbeing difficulties, in addition to unease approximately strength unintended effects a result of construction of steroid derivatives within the tissues.Featuring an esteemed panel of members, this quantity offers an authoritative review of the study bearing on DHEA and the mind. It provides quite a few cutting edge methods and concepts for destiny investigations into the physiological activities of this hormone.
Read Online or Download DHEA and the Brain (Nutrition, Brain, and Behavior) PDF
Similar pharmacy books
The fourth quantity within the six-volume guide of Pharmaceutical production Formulations, this e-book covers semi-solid medicinal drugs. It contains formulations of ointments, creams, gels, and suppositories, from publicly on hand yet broadly dispersed info from FDA New Drug functions (NDA), patent functions, and different resources of well-known and proprietary formulations.
Prescribing and drugs administration is without doubt one of the commonest interventions in overall healthiness care supply and sooner or later becomes a part of the function of many hundreds of thousands of nurses, pharmacists and different professions allied to medication (PAMs). self sustaining and Supplementary Prescribing: a necessary advisor is the 1st publication of its variety and explores a couple of key components for prescribers, together with the moral and felony matters surrounding prescribing, the psychology and sociology of prescribing, prescribing inside a public healthiness context, evidence-based prescribing, prescribing inside of a crew context, easy pharmacology, tracking abilities and drug calculations.
Entire in three volumes. Pharmaceutical know-how. 14 participants.
163 pages, fifty four figures
- Chromatographic Fingerprint Analysis of Herbal Medicines: Thin-layer and High Performance Liquid Chromatography of Chinese Drugs
- drug discovery handbook, 1st Edition
- Generic Drug Product Development: Solid Oral Dosage Forms, Second Edition: Volume 3 (Drugs and the Pharmaceutical Sciences)
- Thermodynamics of Pharmaceutical Systems: An Introduction for Students of Pharmacy
- Chromatography of Pharmaceuticals: Natural, Synthetic, and Recombinant Products (ACS Symposium Series)
Additional info for DHEA and the Brain (Nutrition, Brain, and Behavior)
Et al. (2000) Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: contribution of the DHEAge study to a sociobiomedical issue. Proc. Natl. Acad. Sci. USA, 97, 4279–4284. , de Montigny, C. and Debonnel, G. (1996) Potentiation of neuronal NMDA response induced by dehydroepiandrosterone and its suppression by progesterone: effects mediated via sigma receptors. J. , 16, 1193–1202. -F. -E. (1996) Relationship of dehydroepiandrosterone sulfate in the elderly with functional, psychological, and mental status, and short term mortality: a French community-based study.
1998). These authors also showed that clinical recovery, following a succesful antidepressant treatment, is associated with an enhancement of CSF allopregnanolone concentrations. While the circulating levels of progesterone and allopregnanolone are dramatically reduced in menopause, due to the cessation of ovarian activity, the circulating levels of DHEA and DHEAS are independent from the steroidogenic activity of the ovary (Jones and James, 1987). , 1996), may correlate with the presence and intensity of menopause-associated psychological symptoms.
CONCLUDING REMARKS The results summarized in this chapter support the view that DHEA is a neurosteroid and its synthesis/accumulation appears to be rapidly regulated by brainintrinsic mechanisms involving the activation of intracellular second messenger pathways and ascorbic acid. , 1994; Pierce and Rebec, 1994). , 1998; Compagnone and Mellon, 1998), may be relevant in several pathophysiological aspects in which glutamatergic neurotransmission is involved. e. , 1998), thus far, conflicting results have been obtained in humans when trying either to correlate endogenous DHEA(S) with cognitive function or to assess an effect of DHEA administration on cognition or more generally on well-being (Wolf and Kirschbaum, 1999).