DHEA and the brain by Morfin, Robert

By Morfin, Robert

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Neurobiology of Aging, 23, 135–143. , Steckler, T. (2000) Behavioural analysis of four mouse strains in an anxiety test battery. Behavioral Brain Research, 115, 95–106. Vinatoru, M. (2001) An overview of the ultrasonically assisted extraction of bioactive principles from herbs. Ultrasonics Sonochemistry, 8, 303–313. J. (1997) The use of ultrasound for the extraction of bioactive principles from plant materials. Ultrasonics Sonochemistry, 4, 135–139. E. (2002) Dietary essential fatty acids and brain function: a developmental perspective on mechanisms.

1 GENERAL ACTIVITY The advent of photo beam activity monitoring cages connected to a computerized recording system now allows for the automated and continuous measure of general motor activity in home cages or novel environments. , 1985). Increases or decreases in the level of motor activity and changes in the pattern of activity can provide general but useful information on the effects of nutritional, pharmacological, and environmental manipulations. 2 EXPLORATORY ACTIVITY Measurement of exploratory behavior can take place in a variety of environments.

Many hormones and neurotransmitters have a circadian or pulsatile pattern of release. If one of these endogenous proteins either enhances or inhibits the action of the bioactive ingredient, then careful synchronization of consumption with the peak of a synergistic factor, or trough of an antagonist, has the potential to enhance activity. , 1997). There is also some evidence of diurnal variation in certain types of mental function, including cognition, that appears to be associated with arousal state (Blake, 1967) and may be secondary to hormonal status.

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