Brs Pharmacology (Board Review) by Sandra I. Kim MD PhD, Todd A. Swanson M.D. Ph. D

By Sandra I. Kim MD PhD, Todd A. Swanson M.D. Ph. D

Those quickly and handy flash playing cards will tremendously support scholars in reviewing and studying the $64000 information about pharmacology. all the 269 playing cards deals a short query and resolution, utilizing a set off word to aid scholars memorize and bear in mind right responses. BRS Pharmacology Flash playing cards is a part of a chain of transportable flash playing cards masking microbiology, pathology, and now pharmacology. Designed to accompany BRS Pharmacology , those assessment playing cards also will support scholars enrolled in different uncomplicated technological know-how or pharmacology classes or these getting ready for USMLE Step 1

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Thrombocytopenia (bovine > porcine)—mild, severe (delayed onset; can occur w/heparin resistance → thromboembolism & DIC). Long-term use → osteoporosis. Non-teratogenic, but discontinue prior to delivery. Utility: 1° prevention of DVT after hip replacement surgery. Special Features: Primarily used for venous thromboses. 5x normal PTT is therapeutic. 5 x normal or if therapeutic levels aren’t achieved w/in 24 hr. Few drug interactions. Lower rate of bleeding than w/heparin. : Binds tightly to heparin and rapidly reverses its effects.

Higher incidence of allergic rxns. w/readministration. Pronounced hypotension (usu. transient). Delayed fever and arthralgia. Utility: Treat acute MI (w/in 6 hr. of symptoms), massive PE, acute proximal vein thromboses, occlusion of dialysis access sites and indwelling catheters, occlusion of prosthetic heart valves. Special Features: Best results in pts. that receive therapy < 1 hr. after onset of symptoms and that achieve successful reperfusion. Pts. w/antibodies can develop therapeutic resistance.

S: Salicylates and dicumarol compete for albumin binding sites → marked increase of free levels. Utility: Preferred in treatment of myxedema coma. Treat hypothyroidism and goiter (not due to iodine deficiency or hyperthyroidism). Special Features: 50-75 µg/d. 4x the potency of levothyroxine sodium, but same efficacy. 1 Absorption: Oral → 80-95% bioavailability. Utility: Treat hyperthyroidism, but relapse after single course ≥ 50%. Special Features: 75-100 mg/8 hr (or higher). : Blocks thyroid synthesis.

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