By Sandra I. Kim MD PhD, Todd A. Swanson M.D. Ph. D
Those quickly and handy flash playing cards will tremendously support scholars in reviewing and studying the $64000 information about pharmacology. all the 269 playing cards deals a short query and resolution, utilizing a set off word to aid scholars memorize and bear in mind right responses. BRS Pharmacology Flash playing cards is a part of a chain of transportable flash playing cards masking microbiology, pathology, and now pharmacology. Designed to accompany BRS Pharmacology , those assessment playing cards also will support scholars enrolled in different uncomplicated technological know-how or pharmacology classes or these getting ready for USMLE Step 1
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The fourth quantity within the six-volume instruction manual of Pharmaceutical production Formulations, this booklet covers semi-solid medicines. It comprises formulations of ointments, creams, gels, and suppositories, from publicly to be had yet greatly dispersed details from FDA New Drug purposes (NDA), patent functions, and different resources of conventional and proprietary formulations.
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Thrombocytopenia (bovine > porcine)—mild, severe (delayed onset; can occur w/heparin resistance → thromboembolism & DIC). Long-term use → osteoporosis. Non-teratogenic, but discontinue prior to delivery. Utility: 1° prevention of DVT after hip replacement surgery. Special Features: Primarily used for venous thromboses. 5x normal PTT is therapeutic. 5 x normal or if therapeutic levels aren’t achieved w/in 24 hr. Few drug interactions. Lower rate of bleeding than w/heparin. : Binds tightly to heparin and rapidly reverses its effects.
Higher incidence of allergic rxns. w/readministration. Pronounced hypotension (usu. transient). Delayed fever and arthralgia. Utility: Treat acute MI (w/in 6 hr. of symptoms), massive PE, acute proximal vein thromboses, occlusion of dialysis access sites and indwelling catheters, occlusion of prosthetic heart valves. Special Features: Best results in pts. that receive therapy < 1 hr. after onset of symptoms and that achieve successful reperfusion. Pts. w/antibodies can develop therapeutic resistance.
S: Salicylates and dicumarol compete for albumin binding sites → marked increase of free levels. Utility: Preferred in treatment of myxedema coma. Treat hypothyroidism and goiter (not due to iodine deficiency or hyperthyroidism). Special Features: 50-75 µg/d. 4x the potency of levothyroxine sodium, but same efficacy. 1 Absorption: Oral → 80-95% bioavailability. Utility: Treat hyperthyroidism, but relapse after single course ≥ 50%. Special Features: 75-100 mg/8 hr (or higher). : Blocks thyroid synthesis.