By Anthony J. Hickey, Timothy M. Crowder, Margaret D. Louey, Norman Orr
Exploring the expansion in wisdom of particle houses and the range of technological advances in particle manufacture, this e-book supplies readers the instruments they should comprehend particulate technological know-how and its use within the undefined. The authors disguise particulate fabric, its shape and construction, sampling from our bodies of powder, particle dimension descriptors and records, habit of debris, instrumental research, particle measurement dimension and synergy of followed concepts, actual habit of a powder, and in vitro and in vivo functionality standards. They draw the elements of particulate technology right into a unmarried concise description in their integration within the context of product improvement.
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Extra info for A Guide to Pharmaceutical Particulate Science
Sample text
A. Hersey. 1977. Ordered or random mixing: Choice of system and mixer. Drug Dev. Ind. Pharmacy 3:429–438. ©2003 by Interpharm/CRC Press LLC References 231 Zeng, X. , G. P. Martin, and C. Marriot. 1995. The controlled delivery of drugs to the lungs. Int. J. Pharm. 124:149–164. Zeng, X. , G. P. -K. Tee, and C. Marriott. 1998. The role of fine particle lactose on the dispersion and deaggregation of salbutamol sulphate in an air stream in vitro. Int. J. Pharm. 176:99–110. Zeng, X. , G. P. -K. Tee, A.
2003 by Interpharm/CRC Press LLC Conclusion The structure of crystalline materials has been characterized and can be defined in terms of 230 space lattices that fall into 32 classes of symmetry and seven systems that, in addition to the amorphous state, describe the range of particle morphology. Since regular geometries are a major simplification of true particle morphologies, the effects of specific defects that modify crystal structures to give rise to irregular forms are acknowledged. Particles are produced by a variety of methods.
1992. Dynamic plume-particle size analysis using laser diffraction. Pharm. Tech. 16:109–114. , J. Macur, and J. Marti. 1988. Microscopy. In A guide to materials characterization and chemical analysis, ed. J. Sibilia. New York: VCH Publishers. 137–166. Reist, P. C. 1993a. Aerosol science and technology. New York: McGraw-Hill. Reist, P. C. 1993b. Particle size distributions. Aerosol science and technology. New York: McGraw- Hill. 13–30. , and J. May. 1999. Freeze-drying/lyophilization of pharmaceutical and biological products.