Vagotomy: Latest Advances with Special Reference to Gastric by F. Holle (auth.), Dr. Fritz Holle, Sven Andersson M. D.

By F. Holle (auth.), Dr. Fritz Holle, Sven Andersson M. D. (eds.)

This monograph is a precis of observations accrued during the last ten years on vagal denervation of the tummy and the sensible pathology of the vagotomized abdominal. it really is essentially a continuation of the paintings we (Holle and Heinrich, 1954) all started with fundectomy - the prototype of proximal dener­ vation of the tummy. This was once the place to begin for the advance­ ment of selective proximal vagotomy (SPV). among 1961 and 1964 the secret agent method was once constructed to the level that it may be utilized clinically from January 1,1964. Like so much medical recommendations, the advance came about in different levels. A record at the first 235 surgical instances (1961-1967) seemed in 1968 in F. Holle's certain surgical procedure of the tummy, pp. 508-509, and in 1969 in surgical procedure of the tummy and Duodenum by means of Harkins and Nyhus, 2d variation, pp. 629-634. because that point it's been attainable to illustrate at the foundation of 1200 operated circumstances in addition to animal experiments that the hot approach we brought represents a profitable, nonresecting surgical procedure of gastric and duodenal ulcers. you will need to have a protracted sequence of scientific circumstances from an analogous resource, since it isn't until eventually loads of person observations were accrued situation­ ing issues of prognosis, symptoms and process that's it attainable to examine the relationships among them.

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Extra info for Vagotomy: Latest Advances with Special Reference to Gastric and Duodenal Ulcers Disease

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Z. BioI. Univ. Munich) which docs not bring about complete denervation of the fundus region and effects a functional obstruction of the pylorus followed by dilatation of the stomach and retention of food. It also may be due to differences in the counting method. In using the counting per unit area in the own cases a postop. increase of chief and mucous neck cells can be seen, which results in part from the fact that the diameters of all participating glandular cells diminish after vagotomy. The relationship between the diminution of the Ch and M N cells to the decrease of mucosa thickness cannot be expressed in numbers, since a routine measurement of the cell diameters was not performed .

Two sections of fundic mucosa with formazan granula. Left 5 min incubation, right 30 min incubation. Between both a difference of optical density of 20 % 26 G. E. Holle Change of Parietal-Ceil-Density related to Chief-and Mucous ·Neck-Cells in G DU pre - and post Sel. prox. - Number of Chief· Mucous-Neck and Parietal Cells Density of Parietal-Cells days (absolutValues) % Pat. reI. 54 14,32 66,80 pre-op 43J. K. a' 33J. a' 36J. B. H. J a' 26J. 96 21 4372 /685/571 37831 924 1959 6310/1886/ 1112 DU 312011090/3976 3293/1013/1804 1710/1568/4002 455012282/5552 DU LK.

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